Two named ingredients carry documented cautions. Neither can be weighed, because neither carries a number.
No side effects are listed for Livpure, because the product prints no caution panel at all. Two of its six named ingredients carry documented cautions from named sources: NCCIH records that liver injury has been reported in people using green tea extracts in tablet or capsule form, which matters because this is a liver supplement; and Memorial Sloan Kettering reports that repeated oral berberine significantly decreased CYP2D6, 2C9 and 3A4 activity in human studies, and may worsen jaundice in infants. Neither caution can be assessed by dose, because no amount is published.
Safety assessments are made against amounts. A pharmacist deciding whether an interaction matters wants to know how much. A clinician weighing a liver caution wants to know how much. Anyone comparing a supplement against what they already take wants to know how much.
There are no amounts on this product. So the usual assessment is not available to anybody — not to us, not to your pharmacist, not to your doctor. That is the first thing to understand about this page and it is not a rhetorical flourish.
What is available is what named public sources say about the named ingredients, and that is what this page contains. Two of the six carry cautions specific enough to be worth reading in full.
The product itself prints no caution panel, no age restriction, no pregnancy warning and no storage instruction. Most supplements in this category print all four. Their absence is not evidence that the product is unsafe; it is evidence that the label is doing none of the work a label exists to do.
Take the six ingredient names — silymarin, betaine, berberine, molybdenum, glutathione and camellia sinensis — to a pharmacist before you buy. It is a two-minute conversation and on this product it is the only assessment anybody can make.
Camellia sinensis is the tea plant. In a supplement it means green tea extract, concentrated well beyond anything you would get from drinking tea.
NCCIH states it plainly: “Although uncommon, liver injury has been reported in some people who used green tea products, primarily green tea extracts in tablet or capsule form.”
It adds that individuals carrying a particular genetic variant appear especially susceptible, and that 5 to 15 per cent of Americans carry that variant. Most people have no idea which group they are in.
The word uncommon is NCCIH's and it belongs in any fair summary. These are case reports rather than a common outcome, and millions of people take green tea extract without incident.
What makes it the sharpest point on this site is the combination: an ingredient with a reported liver signal, in a product sold for liver support, at an amount nobody has published, on a label with no caution panel. Any one of those alone would be unremarkable.
NCCIH is equally clear about the other side of the ledger: “definite conclusions cannot yet be reached on whether green tea is helpful for most of the purposes for which it is used.”
Berberine is an alkaloid found in barberry and several other plants, and it has become one of the most popular supplement ingredients of the last decade.
Memorial Sloan Kettering's About Herbs monograph reports: “Repeated oral intake of berberine at a dose used in some studies significantly decreased 2D6, 2C9, and 3A4 activities.”
Those three cytochrome P450 enzymes metabolise a very large share of ordinary prescription medicines. Slowing them down can raise the level of a drug in the body, which is why the monograph warns directly: if you are taking CYP2D6, 2C9 or 3A4 substrate drugs, berberine may decrease their effectiveness.
It carries a second, separate caution that belongs on this page: berberine “may worsen jaundice in infants or result in kernicterus, a condition in which prolonged high bilirubin levels can cause irreversible effects”. That is the specific reason we say plainly that this is not a product for anyone pregnant or nursing.
The same monograph is candid about benefit: most studies are of limited quality, and in the cholesterol literature many were heterogeneous, of low quality or at high risk of bias.
And it states no dose of its own. It refers only to “a dose used in some studies”, which is the honest position when the literature does not converge — and which means there is no figure to compare an unpublished amount against.
NCCIH notes that “some products have been found to contain amounts of silymarin substantially different from what's stated on the label”. On this product there is nothing stated to differ from, which is a worse position rather than a better one.
Betaine anhydrous is approved as Cystadane for homocystinuria at 6 grams a day. That is a drug dose for a rare metabolic disease. Whether this capsule carries grams or milligrams of it is not something anybody outside the company knows.
The brand's own image set names genistein, usually sourced from soy. There is no allergen statement on this product. If you have a soy allergy, ask the order desk before you buy rather than infer anything from a photograph.
Most supplements in this category print a short block on the label: do not exceed the recommended dose; not for use by those under 18 or by pregnant or nursing mothers; consult a physician before use if you are taking medication or have a medical condition; keep out of reach of children; do not use if the safety seal is damaged.
None of that appears on anything we were given for this product. The brief says adults 18 and over, following the label, but the label as supplied to us prints no age restriction at all.
We are not going to write that block ourselves and present it as the manufacturer's, because it is not. What we can say is that everything in it would apply to a product containing berberine and green tea extract, and that its absence is a gap rather than a permission.
Treat this product as an adults-only supplement, not for use in pregnancy or while nursing, and worth a conversation with a pharmacist if you take anything else. That is our advice rather than the label's, and we are labelling it as ours.
Every source above was opened and read. Studies that found nothing are included on purpose.
It is a compilation of what named public sources say about ingredients named on this product, published so you can take it to somebody qualified. If you take prescription medicine or have a liver condition, that person is the one to ask, and asking before the first capsule is better than asking after the first month.
We cannot tell you, and that is the honest answer rather than a cautious one. Safety assessments are made against amounts, and there are no amounts here. Two of the six named ingredients carry documented cautions — green tea extract for reported liver injury and berberine for enzyme interactions and infant jaundice — and neither can be assessed without a number.
It is the sentence on this site we would keep if we had to delete every other one. NCCIH states that “although uncommon, liver injury has been reported in some people who used green tea products, primarily green tea extracts in tablet or capsule form”, and that 5 to 15 per cent of Americans carry a genetic variant that appears to raise the risk. This is a liver supplement, camellia sinensis is named on its own panel, and no amount is published.
Memorial Sloan Kettering reports that repeated oral berberine at a dose used in some studies significantly decreased CYP2D6, 2C9 and 3A4 activity in human studies — three enzyme systems that clear a very large share of ordinary prescription medicines. It also warns that berberine may worsen jaundice in infants. No amount is published here, so no pharmacist can assess it by dose.
Ask a pharmacist before you buy. Berberine is named on the pack, and repeated oral berberine has been reported to significantly decrease CYP2D6, 2C9 and 3A4 activity in human studies. Those enzymes metabolise a long list of common medicines. Take the ingredient names with you, because that is all anyone can give a pharmacist here.
Speak to the clinician who manages it, and take the ingredient list. The specific reason is on this page under green tea extract: NCCIH records reported liver injury with green tea extracts in capsule form. A liver supplement containing that ingredient at an unpublished amount is a conversation for a clinic.
The product prints no age or pregnancy restriction at all, which is itself a gap. Sloan Kettering's berberine monograph warns that it may worsen jaundice in infants or result in kernicterus. On that basis alone this is not a product to take while pregnant or nursing without medical advice.
The brief says adults 18 and over, following the label. The product itself, as far as we were given it, prints no age restriction anywhere.
The listing carries gluten-free and dairy-free badges. Nothing printed supports them, because there is no ingredient line to read. On soy in particular: the brand's own image set names genistein, which is usually sourced from soy, and there is no allergen statement either way. If you have a food allergy, ask before you buy.
NCCIH's summary of the trial evidence is that results in liver disease “have been conflicting or too limited to allow conclusions to be reached”, and that two NIH-supported trials, in hepatitis C and non-alcoholic steatohepatitis, did not show benefits. It also notes that some milk thistle products have been found to contain amounts of silymarin substantially different from the label. This label states no amount at all.
One bottle is 60 capsules. How many days that is depends on a serving size nobody published, so we cannot tell you. The 60-day guarantee runs from purchase either way, and the price is shown at checkout.
Order NowRead the label firstNo price was published to us. We print no figure we have not seen ourselves. · 60-day guarantee from purchase · Not for under 18, pregnancy or nursing